SUBJECT

Analytical Techniques and Methods

Publications on analytical methods used to characterize powders, particles, surfaces, structure, composition, and material behavior.

PUBLICATIONS

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Explore PTI articles, Insights, Know How, and technical publications related to this subject.

  • Photorealistic view inside a pharmaceutical spray drying facility with a stainless steel spray dryer, cyclone separator, product collection lines, inline NIR sensor probes and process monitoring screens.
    4 July 2026

    Spray Drying 4.0: Real-Time PAT, AI Process Control, and What Engineers Actually Gain

    Process analytical technology combined with machine learning is changing residual moisture control and yield prediction in pharmaceutical and food spray drying. The gains are real but bounded, and the off-line test panel has not been replaced.

    Feature Article

  • Technical comparison of copper powder morphologies used in electrification applications, including dendritic, spherical, irregular, and flake copper particles.
    27 June 2026

    Copper Powder for Electrification: Why Morphology, Purity, and Packing Density Are Now Engineering Variables

    Sintered contacts, additive manufactured heat exchangers, EV motor components, and conductive pastes each require a different copper powder. This article explains why morphology, particle size distribution, oxygen content, and packing density are engineering variables, and how to specify them correctly for electrification applications.

    Feature Article

  • Macro view of pharmaceutical powder particles, crystals, and lipid droplets at the interface with an aqueous medium, illustrating surface contact and early dissolution of poorly soluble APIs.
    20 June 2026

    Poorly Soluble APIs: How Surface Contact Shapes Dissolution and Bioavailability

    Poorly soluble APIs now represent the majority of the pharmaceutical development pipeline. Dissolution and oral bioavailability are determined by molecular solubility, surface wetting behavior, solid-state stability, and how the formulation interacts with the GI environment from first contact onward. Amorphous dispersions, lipid systems, nanocrystals, and co-crystals each rely on different surface mechanisms to deliver their intended advantage.

    Feature Article

  • Real-time particle characterization system linking inline powder sensors, process data, and hybrid models for powder process control.
    6 June 2026

    Real-Time Particle Characterization and Process Control

    Real-time particle characterization is moving powder processing from delayed laboratory checks toward [...]

    Feature Article

  • Metal powder feedstock quality assessment in an additive manufacturing lab with fine metal powder, powder bed fusion equipment, and microscopy inspection
    16 May 2026

    Metal Powder Feedstock Quality in Additive Manufacturing: From Particle Behavior to Part Performance

    Metal powder feedstock quality has a direct effect on print stability and [...]

    Feature Article

  • Paint QC bench with drawdown panels, grind gauge, colorimeter, and gloss meter showing dispersion-related coating defects.
    9 May 2026

    When Paint Passes Color QC but Fails in Application

    Paint QC can approve a batch that still behaves badly on the substrate. [...]

    Feature Article

  • Particle size distribution interpretation graphic showing D10, D50, D90, fines, oversize, span, and curve shape in a powder PSD curve.
    2 May 2026

    Particle Size Distribution Interpretation: Reading D10, D50, D90, Fines, and Oversize in Process Context

    Particle size distribution interpretation has the most value when the curve explains [...]

    Know How

  • Thermal gradient segregation in a pilot-scale suspension vessel exposed to uneven heating
    25 April 2026

    Thermal Gradient Segregation: Why Heat Moves Particles

    Thermal gradient segregation begins when one region of a system gets [...]

    Feature Article

  • Acoustic emission for flow blockage prediction sensor mounted near the lower cone outlet of a powder hopper
    18 April 2026

    Acoustic Emission for Flow Blockage Prediction

    Acoustic emission for flow blockage prediction captures high-frequency stress waves generated by [...]

    Feature Article

  • Powder flowability technical illustration comparing normal hopper discharge with arching and pulsing caused by poor venting and unstable flow.
    16 April 2026

    Powder Flowability: Factors and Measurement Techniques

    Powder flowability is not one fixed property. A powder can look free-flowing [...]

    Insights

  • Square hero image showing a powder quality release workflow: sampling, test limits, and a one page lot release decision sheet.
    28 February 2026

    Powder Release Protocol: Sampling Rules and Acceptance Criteria Guide and Check-List

    A powder release protocol is an incoming gate that protects your operating [...]

    Know How

  • Refractory alloy powders for rocket propulsion, photorealistic lab scene with metal powder and AM test coupon
    14 February 2026

    Concentrated Refractory Alloy Powders for Rocket Propulsion

    Concentrated refractory alloy powders for rocket propulsion only create value when you [...]

    Feature Article