SUBJECT

Particle Size Testing

Publications on particle size measurement, method selection, interpretation, and the practical factors that influence reliable particle size data.

PUBLICATIONS

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Explore PTI articles, Insights, Know How, and technical publications related to this subject.

  • Macro view of pharmaceutical powder particles, crystals, and lipid droplets at the interface with an aqueous medium, illustrating surface contact and early dissolution of poorly soluble APIs.
    20 June 2026

    Poorly Soluble APIs: How Surface Contact Shapes Dissolution and Bioavailability

    Poorly soluble APIs now represent the majority of the pharmaceutical development pipeline. Dissolution and oral bioavailability are determined by molecular solubility, surface wetting behavior, solid-state stability, and how the formulation interacts with the GI environment from first contact onward. Amorphous dispersions, lipid systems, nanocrystals, and co-crystals each rely on different surface mechanisms to deliver their intended advantage.

    Feature Article

  • Real-time particle characterization system linking inline powder sensors, process data, and hybrid models for powder process control.
    6 June 2026

    Real-Time Particle Characterization and Process Control

    Real-time particle characterization is moving powder processing from delayed laboratory checks toward [...]

    Feature Article

  • Industrial pneumatic conveying receiver with stainless steel pipework and hopper used for fine powder fluidization.
    30 May 2026

    Fine Powder Fluidization in Pneumatic Conveying and Discharge Control

    Fine powder fluidization can support controlled pneumatic conveying, especially in dense phase [...]

    Feature Article

  • Fine particles between larger powder particles showing how fines in powder behavior affect surface area, contact points, and restricted air paths.
    23 May 2026

    Fines in Powder Behavior: Why Small Amounts Matter

    Fines in powder behavior matter because fine particles add surface area, contact [...]

    Insights

  • Coated particle damage illustration showing intact, abraded, and cracked particles with similar particle size distribution.
    16 May 2026

    Coated Particle Damage Before Particle Size Changes

    Coated particle damage can change performance before particle size distribution shows a [...]

    Insights

  • Metal powder feedstock quality assessment in an additive manufacturing lab with fine metal powder, powder bed fusion equipment, and microscopy inspection
    16 May 2026

    Metal Powder Feedstock Quality in Additive Manufacturing: From Particle Behavior to Part Performance

    Metal powder feedstock quality has a direct effect on print stability and [...]

    Feature Article

  • Paint QC bench with drawdown panels, grind gauge, colorimeter, and gloss meter showing dispersion-related coating defects.
    9 May 2026

    When Paint Passes Color QC but Fails in Application

    Paint QC can approve a batch that still behaves badly on the substrate. [...]

    Feature Article

  • Powder wettability illustration showing poor wetting, trapped air, dry-core clumping, and controlled dispersion in liquid.
    9 May 2026

    Powder Wettability: Why Powders Float, Clump, or Disperse

    Powder wettability controls the first contact between powder and liquid. When liquid [...]

    Insights

  • Particle size distribution interpretation graphic showing D10, D50, D90, fines, oversize, span, and curve shape in a powder PSD curve.
    2 May 2026

    Particle Size Distribution Interpretation: Reading D10, D50, D90, Fines, and Oversize in Process Context

    Particle size distribution interpretation has the most value when the curve explains [...]

    Know How

  • Sieve blinding in powder screening showing near-size wedging, fine-particle coating, agglomeration, and bed overload on a vibrating sieve.
    2 May 2026

    Sieve Blinding: Why Powder Screens Fail Before the Particle Size Spec Does and How to Solve it

    Sieve blinding does more than reduce screening capacity. It changes the [...]

    Insights

  • Three Petri dishes with metal, ceramic, and polymer powders, plus a spatula pouring metallic powder, illustrating powder testing circular economy.
    27 September 2025

    Powder Technologies Within Circular Systems

    The relevance of powder testing for circular economy powder usage. Circular production [...]

    Feature Article

  • AI-assisted material characterization: laser diffraction setup analyzes a powder stream with a camera and PSD histogram on a lab monitor.
    20 September 2025

    Material Characterization with AI-Assisted Analytics

    AI-assisted material characterization speeds testing, strengthens models, and improves inline control. Labs [...]

    Feature Article