Process analytical technology combined with machine learning is changing residual moisture control and yield prediction in pharmaceutical and food spray drying. The gains are real but bounded, and the off-line test panel has not been replaced.
Poorly soluble APIs now represent the majority of the pharmaceutical development pipeline. Dissolution and oral bioavailability are determined by molecular solubility, surface wetting behavior, solid-state stability, and how the formulation interacts with the GI environment from first contact onward. Amorphous dispersions, lipid systems, nanocrystals, and co-crystals each rely on different surface mechanisms to deliver their intended advantage.
Universal dust explosivity criteria fail because explosibility depends [...]
Nano spray drying creates submicron powders from fragile [...]
AI-based in-line particle size monitoring allows real-time tracking [...]
powder deformation behavior under pressure in different ways. [...]
Quantum thinking in powder technology isn’t about physics. [...]
Spray drying technology transforms liquids into powders with [...]
Powder technology is essential in modern blood testing. [...]
Regulatory compliance in powder handling is not [...]
